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Interleukin-1 induces and accelerates human endometrial stromal cell senescence and impairs decidualization via the c-Jun N-terminal kinase pathway

As with much of the rare disease field, rare vascular disease trials face the same structural challenge: patient populations are small and scattered across countries, making cross-border collaboration essential rather than optional

In humans, Trammell and colleagues (2016) reported in Nature Communications that oral NR was observed to raise blood NAD+ in volunteers, with a dose-dependent response